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Prmt5 promotes vascular morphogenesis independently of its methyltransferase activity

During development, the vertebrate vasculature undergoes major growth and remodeling. While the transcriptional cascade underlying blood vessel formation starts to be better characterized, little is known concerning the role and mode of action of epigenetic enzymes during this process. Here, we expl...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Quillien, Aurélie, Gilbert, Guerric, Boulet, Manon, Ethuin, Séverine, Waltzer, Lucas, Vandel, Laurence
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8248709/
https://ncbi.nlm.nih.gov/pubmed/34153034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1009641
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