Role of the inhibitor of serine peptidase 2 (ISP2) of Trypanosoma brucei rhodesiense in parasite virulence and modulation of the inflammatory responses of the host

Trypanosoma brucei rhodesiense is one of the causative agents of Human African Trypanosomiasis (HAT), known as sleeping sickness. The parasite invades the central nervous system and causes severe encephalitis that is fatal if left untreated. We have previously identified ecotin-like inhibitors of se...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:PLoS Negl Trop Dis
Main Authors: Levy, David Jessula, Goundry, Amy, Laires, Raquel S. S., Costa, Tatiana F. R., Novo, Carlos Mendes, Grab, Dennis J., Mottram, Jeremy C., Lima, Ana Paula C. A.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2021
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8248637/
https://ncbi.nlm.nih.gov/pubmed/34153047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0009526
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