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Preclinical Evaluation of B7-H3-Specific Chimeric Antigen Receptor T cells for the Treatment of Acute Myeloid Leukemia

PURPOSE: The development of safe and effective CAR T cell therapy for acute myeloid leukemia (AML) has largely been limited by the concomitant expression of most AML-associated surface antigens on normal myeloid progenitors and by the potential prolonged disruption of normal hematopoiesis by the imm...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Lichtman, Eben, Du, Hongwei, Shou, Peishun, Song, Feifei, Suzuki, Kyogo, Ahn, Sarah, Li, Guangming, Ferrone, Soldano, Su, Lishan, Savoldo, Barbara, Dotti, Gianpietro
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8248479/
https://ncbi.nlm.nih.gov/pubmed/33531429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-20-2540
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