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Impaired Pre‐Motor Circuit Activity and Movement in a Drosophila Model of KCNMA1‐Linked Dyskinesia

BACKGROUND: Paroxysmal dyskinesias (PxDs) are characterized by involuntary movements and altered pre‐motor circuit activity. Causative mutations provide a means to understand the molecular basis of PxDs. Yet in many cases, animal models harboring corresponding mutations are lacking. Here we utilize...

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Detalhes bibliográficos
Publicado no:Mov Disord
Main Authors: Kratschmer, Patrick, Lowe, Simon A., Buhl, Edgar, Chen, Ko‐Fan, Kullmann, Dimitri M., Pittman, Alan, Hodge, James J.L., Jepson, James E.C.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8248399/
https://ncbi.nlm.nih.gov/pubmed/33449381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mds.28479
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