Homocysteine Causes Endothelial Dysfunction via Inflammatory Factor-Mediated Activation of Epithelial Sodium Channel (ENaC)

BACKGROUND: Hyperhomocysteinemia (HHcy) causes cardiovascular diseases via regulating inflammatory responses. We investigated whether and how the epithelial sodium channel (ENaC), a recently identified ion channel in endothelial cells, plays a role in HHcy-induced endothelial dysfunction. METHODS: C...

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Bibliografski detalji
Izdano u:Front Cell Dev Biol
Glavni autori: Liang, Chen, Wang, Qiu-Shi, Yang, Xu, Zhu, Di, Sun, Yu, Niu, Na, Yao, Jie, Dong, Bi-Han, Jiang, Shuai, Tang, Liang-Liang, Lou, Jie, Yu, Chang-Jiang, Shao, Qun, Wu, Ming-Ming, Zhang, Zhi-Ren
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2021
Teme:
Cell and Developmental Biology
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8247579/
https://ncbi.nlm.nih.gov/pubmed/34222246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.672335
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