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Anaphylaxis to drugs: Overcoming mast cell unresponsiveness by fake antigens

Our understanding of IgE‐mediated drug allergy relies on the hapten concept, which is well established in inducing adaptive reactions of the immune system to small molecules like drugs. The role of hapten‐carrier adducts in re‐challenge reactions leading to mast cell degranulation and anaphylaxis is...

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Detalles Bibliográficos
Publicado en:Allergy
Autor Principal: Pichler, Werner J.
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2020
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8247404/
https://ncbi.nlm.nih.gov/pubmed/32780486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/all.14554
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