Pharmacometric analyses to characterize the effect of CSL112 on apolipoprotein A‐I and cholesterol efflux capacity in acute myocardial infarction patients

AIMS: To characterize relationships between apolipoprotein A‐I (apoA‐I) exposure and cholesterol efflux capacity (CEC) and covariate effects following CSL112 (apoA‐I [human]) administration in an integrated population including acute myocardial infarction (AMI) patients. METHODS: A pharmacometric an...

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Pubblicato in:Br J Clin Pharmacol
Autori principali: Zheng, Bo, Duffy, Danielle, Tricoci, Pierluigi, Kastrissios, Helen, Pfister, Marc, Wright, Samuel D., Gille, Andreas, Tortorici, Michael A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2020
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8247400/
https://ncbi.nlm.nih.gov/pubmed/33217027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.14666
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