Concordance Between Tumor and Germline BRCA Status in High-Grade Ovarian Carcinoma Patients in the Phase III PAOLA-1/ENGOT-ov25 Trial

BACKGROUND: PAOLA1 is a phase III study assessing olaparib maintenance therapy in advanced high-grade ovarian carcinoma patients responding to first-line platinum-taxane–based chemotherapy plus bevacizumab as standard of care. Randomization was stratified by treatment outcome and tumor BRCA1/2 statu...

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Pubblicato in:J Natl Cancer Inst
Autori principali: Callens, Céline, Vaur, Dominique, Soubeyran, Isabelle, Rouleau, Etienne, Just, Pierre-Alexandre, Guillerm, Erell, Golmard, Lisa, Goardon, Nicolas, Sevenet, Nicolas, Cabaret, Odile, Harter, Philipp, Gonzalez-Martin, Antonio, Fujiwara, Keiichi, Cecere, Sabrina Chiara, Colombo, Nicoletta, Marth, Christian, Vergote, Ignace, Maenpaa, Johanna, Pujade-Lauraine, Eric, Ray-Coquard, Isabelle
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2020
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8246800/
https://ncbi.nlm.nih.gov/pubmed/33372675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djaa193
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