Phase 1 Study of the Effects of the Tuberculosis Treatment Pretomanid, Alone and in Combination With Moxifloxacin, on the QTc Interval in Healthy Volunteers

Tuberculosis (TB) continues to be a serious threat to public health throughout the world. Newer treatments are needed that could offer simplified regimens with activity against both drug‐sensitive and drug‐resistant bacilli, while optimizing safety. Pretomanid (PA‐824), a nitroimidazooxazine compoun...

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Bibliographic Details
Published in:Clin Pharmacol Drug Dev
Main Authors: Li, Mengchun, Saviolakis, George A., El‐Amin, Wael, Makhene, Mamodikoe K., Osborn, Blaire, Nedelman, Jerry, Yang, Tian J., Everitt, Daniel
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2020
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8246780/
https://ncbi.nlm.nih.gov/pubmed/33378139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpdd.898
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