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A physiologically validated rat model of term birth asphyxia with seizure generation after, not during, brain hypoxia

OBJECTIVE: Birth asphyxia (BA) is often associated with seizures that may exacerbate the ensuing hypoxic–ischemic encephalopathy. In rodent models of BA, exposure to hypoxia is used to evoke seizures, that commence already during the insult. This is in stark contrast to clinical BA, in which seizure...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Epilepsia
Hauptverfasser: Ala‐Kurikka, Tommi, Pospelov, Alexey, Summanen, Milla, Alafuzoff, Aleksander, Kurki, Samu, Voipio, Juha, Kaila, Kai
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8246723/
https://ncbi.nlm.nih.gov/pubmed/33338272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/epi.16790
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