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The role of ALDH2 in tumorigenesis and tumor progression: Targeting ALDH2 as a potential cancer treatment

A major mitochondrial enzyme for protecting cells from acetaldehyde toxicity is aldehyde dehydrogenase 2 (ALDH2). The correlation between ALDH2 dysfunction and tumorigenesis/growth/metastasis has been widely reported. Either low or high ALDH2 expression contributes to tumor progression and varies am...

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Bibliografiske detaljer
Udgivet i:Acta Pharm Sin B
Main Authors: Zhang, Hong, Fu, Liwu
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8245805/
https://ncbi.nlm.nih.gov/pubmed/34221859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.apsb.2021.02.008
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