Reduced beta cell number rather than size is a major contributor to beta cell loss in type 2 diabetes

AIMS/HYPOTHESIS: Type 2 diabetes is characterised by reduced beta cell mass (BCM). However, it remains uncertain whether the reduction in BCM in type 2 diabetes is due to a decrease in size or number of beta cells. Our aim was to examine the impact of beta cell size and number on islet morphology in...

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Publicat a:Diabetologia
Autors principals: Sasaki, Hironobu, Saisho, Yoshifumi, Inaishi, Jun, Watanabe, Yuusuke, Tsuchiya, Tami, Makio, Masayoshi, Sato, Midori, Nishikawa, Masaru, Kitago, Minoru, Yamada, Taketo, Itoh, Hiroshi
Format: Artigo
Idioma:Inglês
Publicat: Springer Berlin Heidelberg 2021
Matèries:
Short Communication
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8245378/
https://ncbi.nlm.nih.gov/pubmed/33938968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-021-05467-7
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