SN38 loaded nanostructured lipid carriers (NLCs); preparation and in vitro evaluations against glioblastoma

SN38 is the active metabolite of irinotecan with 1000-fold greater cytotoxicity compared to the parent drug. Despite the potential, its application as a drug is still seriously limited due to its stability concerns and low solubility in acceptable pharmaceutical solvents. To address these drawbacks...

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Bibliographic Details
Published in:J Mater Sci Mater Med
Main Authors: Shirazi, Ali Sabouri, Varshochian, Reyhaneh, Rezaei, Mahsa, Ardakani, Yalda Hosseinzadeh, Dinarvand, Rassoul
Format: Artigo
Language:Inglês
Published: Springer US 2021
Subjects:
Delivery Systems
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8245372/
https://ncbi.nlm.nih.gov/pubmed/34191134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10856-021-06538-2
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