Basophils balance healing after myocardial infarction via IL-4/IL-13

The inflammatory response after myocardial infarction (MI) is a precisely regulated process that greatly affects subsequent remodeling. Here, we show that basophil granulocytes infiltrated infarcted murine hearts, with a peak occurring between days 3 and 7. Antibody-mediated and genetic depletion of...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Sicklinger, Florian, Meyer, Ingmar Sören, Li, Xue, Radtke, Daniel, Dicks, Severin, Kornadt, Moritz P., Mertens, Christina, Meier, Julia K., Lavine, Kory J., Zhang, Yunhang, Kuhn, Tim Christian, Terzer, Tobias, Patel, Jyoti, Boerries, Melanie, Schramm, Gabriele, Frey, Norbert, Katus, Hugo A., Voehringer, David, Leuschner, Florian
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8245180/
https://ncbi.nlm.nih.gov/pubmed/34196299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI136778
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