Mineralocorticoid receptors dampen glucocorticoid receptor sensitivity to stress via regulation of FKBP5

Responding to different dynamic levels of stress is critical for mammalian survival. Disruption of mineralocorticoid receptor (MR) and glucocorticoid receptor (GR) signaling is proposed to underlie hypothalamic-pituitary-adrenal (HPA) axis dysregulation observed in stress-related psychiatric disorde...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Cell Rep
Hlavní autoři: Hartmann, Jakob, Bajaj, Thomas, Klengel, Claudia, Chatzinakos, Chris, Ebert, Tim, Dedic, Nina, McCullough, Kenneth M., Lardenoije, Roy, Joëls, Marian, Meijer, Onno C., McCann, Katharine E., Dudek, Serena M., Sarabdjitsingh, R. Angela, Daskalakis, Nikolaos P., Klengel, Torsten, Gassen, Nils C., Schmidt, Mathias V., Ressler, Kerry J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2021
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8244946/
https://ncbi.nlm.nih.gov/pubmed/34077736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2021.109185
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky