Substrate recognition mechanism of tRNA-targeting ribonuclease, colicin D, and an insight into tRNA cleavage-mediated translation impairment

Colicin D is a plasmid-encoded bacteriocin that specifically cleaves tRNA(Arg) of sensitive Escherichia coli cells. E. coli has four isoaccepting tRNA(Arg)s; the cleavage occurs at the 3′ end of anticodon-loop, leading to translation impairment in the sensitive cells. tRNAs form a common L-shaped st...

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Détails bibliographiques
Publié dans:RNA Biol
Auteurs principaux: Ogawa, Tetsuhiro, Takahashi, Kazutoshi, Ishida, Wataru, Aono, Toshihiro, Hidaka, Makoto, Terada, Tohru, Masaki, Haruhiko
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 2020
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8244772/
https://ncbi.nlm.nih.gov/pubmed/33211605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2020.1838782
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