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Experimental Design and Sample Size Considerations in Longitudinal MRI Based Biomarker Detection for Multiple Sclerosis

Several modeling approaches have been developed to quantify differences in multiple sclerosis (MS) lesion evolution on magnetic resonance imaging (MRI) to identify the effect of treatment on disease progression. These studies have limited clinical applicability due to onerous scan frequency and leng...

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Bibliographische Detailangaben
Veröffentlicht in:Stat Methods Med Res
Hauptverfasser: Hu, Menghan, Schindler, Matthew K., Dewey, Blake E., Reich, Daniel S., Shinohara, Russell T., Eloyan, Ani
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8244615/
https://ncbi.nlm.nih.gov/pubmed/32070238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0962280220904392
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