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Sirtuin 3 deficiency promotes acute kidney injury induced by sepsis via mitochondrial dysfunction and apoptosis
OBJECTIVE(S): To explore the regulation mechanism of Sirtuin 3 (SIRT3) on the mitochondrial function and apoptosis of acute kidney injury (AKI) in septic mice. MATERIALS AND METHODS: The sepsis-induced AKI model was constructed in the wild-type and SIRT3 knockout (KO) mice, and the levels of serum c...
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| Izdano u: | Iran J Basic Med Sci |
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| Glavni autori: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Mashhad University of Medical Sciences
2021
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8244614/ https://ncbi.nlm.nih.gov/pubmed/34249270 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22038/ijbms.2021.54905.12312 |
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