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Spatial progression and molecular heterogeneity of IDH-mutant glioblastoma determined by DNA methylation-based mapping

Glioblastoma (GBM) is the most common malignant primary central nervous system (CNS) neoplasm in adults, and has an almost universally poor prognosis. Recently, an emphasis on genetic and epigenetic profiling has revealed a number of molecular features useful in the diagnostic and prognostic classif...

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Detalhes bibliográficos
Publicado no:Acta Neuropathol Commun
Main Authors: Lyon, James F., Vasudevaraja, Varshini, Mirchia, Kanish, Walker, Jamie M., Corona, Robert J., Chin, Lawrence S., Tran, Ivy, Snuderl, Matija, Richardson, Timothy E., Viapiano, Mariano S.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8243907/
https://ncbi.nlm.nih.gov/pubmed/34193272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-021-01221-7
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