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Head and Neck Rhabdomyosarcoma Harboring TFCP2 Fusions and ALK overexpression: A Clinicopathologic and Molecular Analysis of 11 cases

BACKGROUND: Primary intraosseous rhabdomyosarcoma (RMS) is a rare entity defined by EWSR1/FUS-TFCP2 or less commonly MEIS1-NCOA2 fusions. The lesions often display a hybrid spindle and epithelioid phenotype, frequently co-express myogenic markers, ALK and cytokeratin, and show a striking propensity...

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Detalhes bibliográficos
Publicado no:Histopathology
Main Authors: Xu, Bin, Suurmeijer, Albert JH, Agaram, Narasimhan P, Zhang, Lei, Antonescu, Cristina R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8243398/
https://ncbi.nlm.nih.gov/pubmed/33382123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/his.14323
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