Direct Mapping of Phospholipid Ferroptotic Death Signals in Cells and Tissues by Gas Cluster Ion Beam Secondary Ion Mass Spectrometry (GCIB-SIMS)

Peroxidized phosphatidylethanolamine (PEox) species have been identified by liquid chromatography mass spectrometry (LC-MS) as predictive biomarkers of ferroptosis, a new program of regulated cell death. However, the presence and subcellular distribution of PEox in specific cell types and tissues ha...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Sparvero, Louis J., Tian, Hua, Amoscato, Andrew A., Sun, Wan-Yang, Anthonymuthu, Tamil S., Tyurina, Yulia Y., Kapralov, Oleksandr, Javadov, Sabzali, He, Rong-Rong, Watkins, Simon C., Winograd, Nicholas, Kagan, Valerian E., Bayır, Hülya
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8243396/
https://ncbi.nlm.nih.gov/pubmed/33684237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.202102001
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