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Renal neoplasms in tuberous sclerosis mice are neurocristopathies

Tuberous sclerosis (TS) is a rare disorder exhibiting multi-systemic benign neoplasms. We hypothesized the origin of TS neoplastic cells derived from the neural crest given the heterogeneous ecto-mesenchymal phenotype of the most common TS neoplasms. To test this hypothesis, we employed Cre-loxP lin...

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Detalhes bibliográficos
Publicado no:iScience
Main Authors: Unachukwu, Uchenna, Shiomi, Takayuki, Goldklang, Monica, Chada, Kiran, D'Armiento, Jeanine
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8243016/
https://ncbi.nlm.nih.gov/pubmed/34222844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2021.102684
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