The ETS Inhibitor YK-4-279 Suppresses Thyroid Cancer Progression Independent of TERT Promoter Mutations

Hotspot mutations in the core promoter region of the telomerase reverse transcriptase (TERT) gene have been well established to associate with aggressive clinical characteristics, radioiodine refractory, tumor recurrence, and mortality in thyroid cancer. Several E-twenty-six (ETS) transcription fact...

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Vydáno v:Front Oncol
Hlavní autoři: Xue, Junyu, Li, Shiyong, Shi, Peijie, Chen, Mengke, Yu, Shuang, Hong, Shubin, Li, Yanbing, Liu, Rengyun, Xiao, Haipeng
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021
Témata:
Oncology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8242932/
https://ncbi.nlm.nih.gov/pubmed/34221969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.649323
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