Development of a Novel Multi-Epitope Vaccine Against Crimean-Congo Hemorrhagic Fever Virus: An Integrated Reverse Vaccinology, Vaccine Informatics and Biophysics Approach

Crimean-Congo hemorrhagic fever (CCHF) is a highly severe and virulent viral disease of zoonotic origin, caused by a tick-born CCHF virus (CCHFV). The virus is endemic in many countries and has a mortality rate between 10% and 40%. As there is no licensed vaccine or therapeutic options available to...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Tahir Ul Qamar, Muhammad, Ismail, Saba, Ahmad, Sajjad, Mirza, Muhammad Usman, Abbasi, Sumra Wajid, Ashfaq, Usman Ali, Chen, Ling-Ling
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8242340/
https://ncbi.nlm.nih.gov/pubmed/34220816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.669812
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