3-Alkenyl-2-oxindoles: Synthesis, antiproliferative and antiviral properties against SARS-CoV-2

Sets of 3-alkenyl-2-oxindoles (6,10,13) were synthesized in a facile synthetic pathway through acid dehydration (EtOH/HCl) of the corresponding 3-hydroxy-2-oxoindolines (5,9,12). Single crystal (10a,c) and powder (12a,26f) X-ray studies supported the structures. Compounds 6c and 10b are the most eff...

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Bibliografiset tiedot
Julkaisussa:Bioorg Chem
Päätekijät: Girgis, Adel S., Panda, Siva S., Srour, Aladdin M., Abdelnaser, Anwar, Nasr, Soad, Moatasim, Yassmin, Kutkat, Omnia, El Taweel, Ahmed, Kandeil, Ahmed, Mostafa, Ahmed, Ali, Mohamed A., Fawzy, Nehmedo G., Bekheit, Mohamed S., Shalaby, ElSayed M., Gigli, Lara, Fayad, Walid, Soliman, Ahmed A.F.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Published by Elsevier Inc. 2021
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC8241580/
https://ncbi.nlm.nih.gov/pubmed/34243074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bioorg.2021.105131
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