3-Alkenyl-2-oxindoles: Synthesis, antiproliferative and antiviral properties against SARS-CoV-2

Sets of 3-alkenyl-2-oxindoles (6,10,13) were synthesized in a facile synthetic pathway through acid dehydration (EtOH/HCl) of the corresponding 3-hydroxy-2-oxoindolines (5,9,12). Single crystal (10a,c) and powder (12a,26f) X-ray studies supported the structures. Compounds 6c and 10b are the most eff...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Bioorg Chem
Main Authors: Girgis, Adel S., Panda, Siva S., Srour, Aladdin M., Abdelnaser, Anwar, Nasr, Soad, Moatasim, Yassmin, Kutkat, Omnia, El Taweel, Ahmed, Kandeil, Ahmed, Mostafa, Ahmed, Ali, Mohamed A., Fawzy, Nehmedo G., Bekheit, Mohamed S., Shalaby, ElSayed M., Gigli, Lara, Fayad, Walid, Soliman, Ahmed A.F.
Format: Artigo
Jezik:Inglês
Izdano: Published by Elsevier Inc. 2021
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8241580/
https://ncbi.nlm.nih.gov/pubmed/34243074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bioorg.2021.105131
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