Preparation and evaluation of Vinpocetine self-emulsifying pH gradient release pellets

The main objective of this study was to develop a pH gradient release pellet with self-emulsifying drug delivery system (SEDDS), which could not only improve the oral bioavailability of Vinpocetine (VIN), a poor soluble drug, but reduce the fluctuation of plasma concentration. First, the liquid VIN...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Drug Deliv
Main Authors: Liu, Mengqi, Zhang, Shiming, Cui, Shuxia, Chen, Fen, Jia, Lianqun, Wang, Shu, Gai, Xiumei, Li, Pingfei, Yang, Feifei, Pan, Weisan, Yang, Xinggang
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2017
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8241196/
https://ncbi.nlm.nih.gov/pubmed/29043863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10717544.2017.1388453
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