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SS-31 peptide enables mitochondrial targeting drug delivery: a promising therapeutic alteration to prevent hair cell damage from aminoglycosides

Aminoglycoside-induced hearing loss stems from damage or loss of mechanosensory hair cells in the inner ear. Intrinsic mitochondrial cell death pathway plays a key role in that cellular dysfunction for which no proven effective therapies against oto-toxicities exist. Therefore, the aim of the presen...

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Detalles Bibliográficos
Publicado en:Drug Deliv
Main Authors: Kuang, Xiao, Zhou, Shuang, Guo, Weiling, Wang, Zhenjie, Sun, Yanhui, Liu, Hongzhuo
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8241023/
https://ncbi.nlm.nih.gov/pubmed/29214897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10717544.2017.1402220
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