DHT causes liver steatosis via transcriptional regulation of SCAP in normal weight female mice

Hyperandrogenemia (HA) is a hallmark of polycystic ovary syndrome (PCOS) and is an integral element of non-alcoholic fatty liver disease (NALFD) in females. Administering low-dose dihydrotestosterone (DHT) induced a normal weight PCOS-like female mouse model displaying NAFLD. The molecular mechanism...

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Publicado en:J Endocrinol
Autores principales: Seidu, Tina, McWhorter, Patrick, Myer, Jessie, Alamgir, Rabita, Eregha, Nicole, Bogle, Dilip, Lofton, Taylor, Ecelbarger, Carolyn, Andrisse, Stanley
Formato: Artigo
Lenguaje:Inglês
Publicado: Bioscientifica Ltd 2021
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8240729/
https://ncbi.nlm.nih.gov/pubmed/34060475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/JOE-21-0040
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