Humanized anti-TLR4 monoclonal antibody ameliorates lipopolysaccharide-related acute kidney injury by inhibiting TLR4/NF-κB signaling

A humanized anti-Toll-like receptor 4 (TLR4) monoclonal antibody (mAb) was previously produced using phage antibody library technology, and it was found that the mAb could effectively ameliorate lipopolysaccharide (LPS)-induced damage in macrophages. The present study investigated the protective eff...

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Bibliographic Details
Published in:Mol Med Rep
Main Authors: Zhang, Qiuhua, Wang, Liang, Wu, Mian, Liu, Xiaobin, Zhu, Yushan, Zhu, Jin, Xing, Changying
Format: Artigo
Language:Inglês
Published: D.A. Spandidos 2021
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8240183/
https://ncbi.nlm.nih.gov/pubmed/34184086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2021.12245
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