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TGF-β Signaling in Pancreatic Islet β Cell Development and Function

Pancreatic islet beta cells (β-cells) synthesize and secrete insulin in response to rising glucose levels and thus are a prime target in both major forms of diabetes. Type 1 diabetes ensues due to autoimmune destruction of β-cells. On the other hand, the prevailing insulin resistance and hyperglycem...

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Publicado en:Endocrinology
Autores principales: Lee, Ji-Hyun, Lee, Ji-Hyeon, Rane, Sushil G
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8240135/
https://ncbi.nlm.nih.gov/pubmed/33349851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/endocr/bqaa233
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