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Angiotensin‐II type 2 receptor activation modulates renal neprilysin and coronavirus receptor angiotensin converting enzyme‐2 expression and activity in obese rats fed high salt diet

Neprilysin and coronavirus receptor angiotensin‐converting enzyme‐2 (ACE2) are peptidases critically involved in the breakdown of deleterious angiotensin‐II and the formation of protective angiotensin‐(1‐7). A disintegrin and metalloproteinase‐17 (ADAM17) is involved in the shedding of neprilysin an...

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Bibliographische Detailangaben
Veröffentlicht in:FASEB J
Hauptverfasser: Patel, Sanket, Hussain, Tahir
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Federation of American Societies for Experimental Biology 2021
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8239623/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fasebj.2021.35.S1.02151
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