Free-radical cyclization approach to polyheterocycles containing pyrrole and pyridine rings

A wide range of derivatives with new pyrido[2,1-a]pyrrolo[3,4-c]isoquinoline skeleton was synthesized by free-radical intramolecular cyclization of o-bromophenyl-substituted pyrrolylpyridinium salts using the (TMS)(3)SiH/AIBN system. The cyclization provides generally good yields of pyrido[2,1-a]pyr...

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Detalhes bibliográficos
Publicado no:Beilstein J Org Chem
Main Authors: Mosiagin, Ivan P, Tomashenko, Olesya A, Spiridonova, Dar’ya V, Novikov, Mikhail S, Tunik, Sergey P, Khlebnikov, Alexander F
Formato: Artigo
Idioma:Inglês
Publicado em: Beilstein-Institut 2021
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Full Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8239278/
https://ncbi.nlm.nih.gov/pubmed/34239616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.17.105
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