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One-step synthesis of imidazoles from Asmic (anisylsulfanylmethyl isocyanide)

Substituted imidazoles are readily prepared by condensing the versatile isocyanide Asmic, anisylsulfanylmethylisocyanide, with nitrogenous π-electrophiles. Deprotonating Asmic with lithium hexamethyldisilazide effectively generates a potent nucleophile that efficiently intercepts nitrile and imine e...

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Detalhes bibliográficos
Publicado no:Beilstein J Org Chem
Main Authors: Mueller, Louis G, Chao, Allen, AlWedi, Embarek, Fleming, Fraser F
Formato: Artigo
Idioma:Inglês
Publicado em: Beilstein-Institut 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8239262/
https://ncbi.nlm.nih.gov/pubmed/34239617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.17.106
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