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Computational drug repositioning identifies statins as a modifier of prognostic genetic expression signatures and metastatic behavior in melanoma

Despite advances in melanoma treatment, more than 70% of patients with distant metastasis die within 5 years. Proactive treatment of early melanoma to prevent metastasis could save lives and reduce overall healthcare costs. Currently, there are no treatments specifically designed to prevent early me...

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Detalhes bibliográficos
Publicado no:J Invest Dermatol
Main Authors: Yu, Wesley Y., Hill, Sheena T., Chan, E. Ricky, Pink, John J., Cooper, Kevin, Leachman, Sancy, Lund, Amanda W., Kulkarni, Rajan, Bordeaux, Jeremy S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8238797/
https://ncbi.nlm.nih.gov/pubmed/33417917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jid.2020.12.015
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