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Novel ZAP-70-Related Immunodeficiency Presenting with Epstein–Barr Virus Lymphoproliferative Disorder and Hemophagocytic Lymphohistiocytosis

Zeta-chain-associated protein kinase 70 (ZAP-70) plays an integral role in the T-cell antigenic receptor complex. A deficiency of this kinase leads to a phenotype of severe combined immunodeficiency, while hypomorphic mutations of the kinase lead to more mild immunodeficiency phenotypes. We present...

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Detalhes bibliográficos
Publicado no:Case Reports Immunol
Main Authors: Forster, Moriah, Moran, Timothy, Beaven, Anne, Voorhees, Timothy
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8238617/
https://ncbi.nlm.nih.gov/pubmed/34239742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2021/6587323
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