Genetic sensitivity analysis: Adjusting for genetic confounding in epidemiological associations

Associations between exposures and outcomes reported in epidemiological studies are typically unadjusted for genetic confounding. We propose a two-stage approach for estimating the degree to which such observed associations can be explained by genetic confounding. First, we assess attenuation of exp...

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Veröffentlicht in:PLoS Genet
Hauptverfasser: Pingault, Jean-Baptiste, Rijsdijk, Frühling, Schoeler, Tabea, Choi, Shing Wan, Selzam, Saskia, Krapohl, Eva, O’Reilly, Paul F., Dudbridge, Frank
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2021
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8238188/
https://ncbi.nlm.nih.gov/pubmed/34115765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1009590
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