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Optical clearing reveals TNBS-induced morphological changes of VGLUT2-positive nerve fibers in mouse colorectum

Colorectal hypersensitivity and sensitization of both mechanosensitive and mechanically insensitive afferents develop after intracolonic instillation of 2,4,6-trinitrobenzenesulfonic acid (TNBS) in the mouse, a model of postinfectious irritable bowel syndrome. In mice in which ∼80% of extrinsic colo...

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Detalhes bibliográficos
Publicado no:Am J Physiol Gastrointest Liver Physiol
Main Authors: Guo, Tiantian, Patel, Shivam, Shah, Dhruv, Chi, Ling, Emadi, Sharareh, Pierce, David M., Han, Martin, Brumovsky, Pablo R., Feng, Bin
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8238166/
https://ncbi.nlm.nih.gov/pubmed/33533318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00363.2020
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