Counterion Optimization Dramatically Improves Selectivity for Phosphopeptides and Glycopeptides in Electrostatic Repulsion-Hydrophilic Interaction Chromatography (ERLIC)

A well-hydrated counterion can selectively and dramatically increase retention of a charged analyte in hydrophilic interaction chromatography (HILIC). The effect is enhanced if the column is charged, as in electrostatic repulsion-hydrophilic interaction chromatography (ERLIC). This combination was e...

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Veröffentlicht in:Anal Chem
Hauptverfasser: Cui, Yusi, Tabang, Dylan Nicholas, Zhang, Zishan, Ma, Min, Alpert, Andrew J., Li, Lingjun
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8237654/
https://ncbi.nlm.nih.gov/pubmed/34042420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.1c00615
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