Rtt105 promotes high-fidelity DNA replication and repair by regulating the single-stranded DNA-binding factor RPA

Single-stranded DNA (ssDNA) covered with the heterotrimeric Replication Protein A (RPA) complex is a central intermediate of DNA replication and repair. How RPA is regulated to ensure the fidelity of DNA replication and repair remains poorly understood. Yeast Rtt105 is an RPA-interacting protein req...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Wang, Xuejie, Dong, Yang, Zhao, Xiaocong, Li, Jinbao, Lee, Jordan, Yan, Zhenxin, Yang, Shuangshuang, Wu, Wenqiang, Hou, Ximiao, Liu, Guangxue, Zhang, Yueyue, Song, Lun, Cai, Gang, Li, Qing, Ira, Grzegorz, Zhang, Xinghua, Chen, Xuefeng
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2021
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8237652/
https://ncbi.nlm.nih.gov/pubmed/34140406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2106393118
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