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Dental effects of enzyme replacement therapy in case of childhood-type hypophosphatasia

BACKGROUND: Hypophosphatasia (HPP), a skeletal disease characterized by hypomineralization of bone and teeth, is caused by an ALPL gene mutation that leads to low activity of the tissue non-specific alkaline phosphatase enzyme. Although enzyme replacement therapy (ERT) was recently introduced for af...

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Detalhes bibliográficos
Publicado no:BMC Oral Health
Main Authors: Okawa, Rena, Kokomoto, Kazuma, Nakano, Kazuhiko
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8237502/
https://ncbi.nlm.nih.gov/pubmed/34176466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12903-021-01673-2
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