Investigating the response of paediatric leukaemia‐propagating cells to BCL‐2 inhibitors

Relapse of paediatric acute lymphoblastic leukaemia (ALL) may occur due to persistence of resistant cells with leukaemia‐propagating ability (LPC). In leukaemia, the balance of B‐cell lymphoma‐2 (BCL‐2) family proteins is disrupted, promoting survival of malignant cells and possibly LPC. A direct co...

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Dades bibliogràfiques
Publicat a:Br J Haematol
Autors principals: Diamanti, Paraskevi, Ede, Benjamin C., Dace, Phoebe EI, Barendt, William J., Cox, Charlotte V., Hancock, Jeremy P., Moppett, John P., Blair, Allison
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2020
Matèries:
Haematological Malignancy ‐ Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8237230/
https://ncbi.nlm.nih.gov/pubmed/32452017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bjh.16773
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