Tenascin-C-mediated suppression of extracellular matrix adhesion force promotes entheseal new bone formation through activation of Hippo signalling in ankylosing spondylitis

OBJECTIVES: The aim of this study was to identify the role of tenascin-C (TNC) in entheseal new bone formation and to explore the underlying molecular mechanism. METHODS: Ligament tissue samples were obtained from patients with ankylosing spondylitis (AS) during surgery. Collagen antibody-induced ar...

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Detalhes bibliográficos
Publicado no:Ann Rheum Dis
Main Authors: Li, Zihao, Chen, Siwen, Cui, Haowen, Li, Xiang, Chen, Dongying, Hao, Wenjun, Wang, Jianru, Li, Zemin, Zheng, Zhaomin, Zhang, Zhongping, Liu, Hui
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2021
Assuntos:
Spondyloarthritis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8237173/
https://ncbi.nlm.nih.gov/pubmed/33858850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2021-220002
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