Expression of ACE2, Soluble ACE2, Angiotensin I, Angiotensin II and Angiotensin-(1-7) Is Modulated in COVID-19 Patients

The etiological agent of COVID-19 SARS-CoV-2, is primarily a pulmonary-tropic coronavirus. Infection of alveolar pneumocytes by SARS-CoV-2 requires virus binding to the angiotensin I converting enzyme 2 (ACE2) monocarboxypeptidase. ACE2, present on the surface of many cell types, is known to be a re...

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Bibliografiske detaljer
Udgivet i:Front Immunol
Main Authors: Osman, Ikram Omar, Melenotte, Cléa, Brouqui, Philippe, Million, Matthieu, Lagier, Jean-Christophe, Parola, Philippe, Stein, Andréas, La Scola, Bernard, Meddeb, Line, Mege, Jean-Louis, Raoult, Didier, Devaux, Christian A.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8236950/
https://ncbi.nlm.nih.gov/pubmed/34194422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.625732
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