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Transcriptomic analysis reveals receptor subclass-specific immune regulation of CD8+ T cells by opioids

Opioid peptides are released at sites of injury, and their cognate G-protein coupled opioid receptors (OR) are expressed on immune cells. Exposure of human circulating CD8+ T cells to selective OR agonists differentially regulates thousands of genes. Gene set enrichment analysis reveals that µ-OR mo...

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Pubblicato in:Immunohorizons
Autori principali: Mazahery, Claire, Valadkhan, Saba, Levine, Alan D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8236285/
https://ncbi.nlm.nih.gov/pubmed/32675085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/immunohorizons.2000019
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