Radiopharmaceutical Formulation and Preclinical Testing of (68)Ga-Labeled DOTA-MGS5 for the Regulatory Approval of a First Exploratory Clinical Trial

The new minigastrin analog DOTA-MGS5 is a promising new candidate for targeting cholecystokinin-2 receptor (CCK2R)-expressing tumors. To enable the clinical translation of PET/CT imaging using (68)Ga-labeled DOTA-MGS5, different quality and safety aspects need to be considered to comply with the reg...

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Vydáno v:Pharmaceuticals (Basel)
Hlavní autoři: Hörmann, Anton A., Klingler, Maximilian, Rangger, Christine, Mair, Christian, Decristoforo, Clemens, Uprimny, Christian, Virgolini, Irene J., von Guggenberg, Elisabeth
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8235783/
https://ncbi.nlm.nih.gov/pubmed/34208516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph14060575
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