Kinase Inhibitors of DNA-PK, ATM and ATR in Combination with Ionizing Radiation Can Increase Tumor Cell Death in HNSCC Cells While Sparing Normal Tissue Cells

(1) Kinase inhibitors (KI) targeting components of the DNA damage repair pathway are a promising new type of drug. Combining them with ionizing radiation therapy (IR), which is commonly used for treatment of head and neck tumors, could improve tumor control, but could also increase negative side eff...

Full description

Saved in:
Bibliographic Details
Published in:Genes (Basel)
Main Authors: Faulhaber, Eva-Maria, Jost, Tina, Symank, Julia, Scheper, Julian, Bürkel, Felix, Fietkau, Rainer, Hecht, Markus, Distel, Luitpold V.
Format: Artigo
Language:Inglês
Published: MDPI 2021
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8235750/
https://ncbi.nlm.nih.gov/pubmed/34204447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes12060925
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items