Gender-Specific Efficacy Revealed by Head-to-Head Comparison of Pasireotide and Octreotide in a Representative In Vivo Model of Nonfunctioning Pituitary Tumors

SIMPLE SUMMARY: No effective medical therapy exists for residual/recurrent nonfunctioning pituitary tumors (NFPTs). First-generation somatostatin analogs (SSAs) like octreotide targeting somatostatin receptor type 2 (SSTR2) are the mainstay therapy for functioning PTs, but have shown little effect i...

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Published in:Cancers (Basel)
Main Authors: Gulde, Sebastian, Wiedemann, Tobias, Schillmaier, Mathias, Valença, Isabel, Lupp, Amelie, Steiger, Katja, Yen, Hsi-Yu, Bäuerle, Stephen, Notni, Johannes, Luque, Raul, Schmid, Herbert, Schulz, Stefan, Ankerst, Donna P., Schilling, Franz, Pellegata, Natalia S.
Format: Artigo
Language:Inglês
Published: MDPI 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8235746/
https://ncbi.nlm.nih.gov/pubmed/34205778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13123097
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