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Long-Chain Acylcarnitines Decrease the Phosphorylation of the Insulin Receptor at Tyr1151 Through a PTP1B-Dependent Mechanism

The accumulation of lipid intermediates may interfere with energy metabolism pathways and regulate cellular energy supplies. As increased levels of long-chain acylcarnitines have been linked to insulin resistance, we investigated the effects of long-chain acylcarnitines on key components of the insu...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Vilks, Karlis, Videja, Melita, Makrecka-Kuka, Marina, Katkevics, Martins, Sevostjanovs, Eduards, Grandane, Aiga, Dambrova, Maija, Liepinsh, Edgars
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8235348/
https://ncbi.nlm.nih.gov/pubmed/34208786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22126470
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