Preclinical Assessment of Ursolic Acid Loaded into Nanostructured Lipid Carriers in Experimental Visceral Leishmaniasis

Ursolic acid, a triterpene produced by plants, displayed leishmanicidal activity in vitro and in vivo; however, the low solubility of this triterpene limits its efficacy. To increase the activity of ursolic acid (UA), this triterpene was entrapped in nanostructured lipid carriers (UA-NLC), physical-...

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Vydáno v:Pharmaceutics
Hlavní autoři: Jesus, Jéssica Adriana, Sousa, Ilza Maria Oliveira, da Silva, Thays Nicolli Fragoso, Ferreira, Aurea Favero, Laurenti, Márcia Dalastra, Antonangelo, Leila, Faria, Caroline Silvério, da Costa, Paulo Cardoso, de Carvalho Ferreira, Domingos, Passero, Luiz Felipe Domingues
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8235317/
https://ncbi.nlm.nih.gov/pubmed/34205283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics13060908
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