Optogenetically Controlled Activity Pattern Determines Survival Rate of Developing Neocortical Neurons

A substantial proportion of neurons undergoes programmed cell death (apoptosis) during early development. This process is attenuated by increased levels of neuronal activity and enhanced by suppression of activity. To uncover whether the mere level of activity or also the temporal structure of elect...

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Publicat a:Int J Mol Sci
Autors principals: Wong Fong Sang, I. Emeline, Schroer, Jonas, Halbhuber, Lisa, Warm, Davide, Yang, Jenq-Wei, Luhmann, Heiko J., Kilb, Werner, Sinning, Anne
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2021
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8235092/
https://ncbi.nlm.nih.gov/pubmed/34205237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22126575
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